Biotinylated LILRB5/CD85c/LIR8 His&Avi Tag Protein, Human
SKU: 92276830568

Biotinylated LILRB5/CD85c/LIR8 His&Avi Tag Protein, Human

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Description

Biotinylated LILRB5/CD85c/LIR8 His&Avi Tag Protein, HumanProduct Specification Species Human Synonyms LILRB5,CD85c,LIR 8 Accession O75023 1 Amino Acid Sequence Gly24 Gly458, with C terminal His&Avi Expression System HEK293 Molecular Weight 72 80kDa (Reducing) Purity >95% by SDS PAGE Endotoxin <1EU g Conjugation Biotin Tag Avi Tag, His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4, 5% trehalose Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water after

Product Specification


Species Human
Synonyms LILRB5,CD85c,LIR-8
Accession O75023-1
Amino Acid Sequence Gly24-Gly458, with C-terminal His&Avi
Expression System HEK293
Molecular Weight

72-80kDa (Reducing)

Purity >95% by SDS-PAGE
Endotoxin <1EU/μg
Conjugation Biotin
Tag Avi Tag, His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4, 5% trehalose
Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

TEDLA N, LEE CW, BORGES L, et al. Differential expression of leukocyte immunoglobulin-like receptors on cord blood-derived human mast cell progenitors and mature mast cells.[J]. Journal of Leukocyte Biology: An Official Publication of the Reticuloendothelial Society,2008,83(2):334-343.

Background

LILRB5, also known as CD85c and LIR-8, consists of an extracellular domain (ECD) with four Ig-like domains, a transmembrane segment, and a cytoplasmic domain with two immunoreceptor tyrosine-based inhibitory motifs (ITIM). LILRB5 is expressed in mast cell granules and the release of soluble LILRB5 following IgE FcR-dependent stimulation, which has potential for amplification of mast cell-dependent, inflammatory responses. The mRNA expression of all LILRB family members was significantly associated with the infiltration of B cells, CD8+ T cells, CD4+ T cells, macrophages, neutrophils, and dendritic cells in liver cancer.

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SKU: 92276830568

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