FITC Human Anti-Human GM-CSF Antibody (S-2816)
SKU: 6360789387

FITC Human Anti-Human GM-CSF Antibody (S-2816)

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Description

FITC Human Anti-Human GM-CSF Antibody (S-2816)Product Specification Host Human Antigen GM CSF Synonyms Granulocyte macrophage colony stimulating factor; Colony stimulating factor (CSF); Molgramostin; Sargramostim; GMCSF; CSF2 Location Secreted Accession P04141 Clone Number S 2816 Antibody Type Recombinant mAb Application ICFCM Reactivity Hu Positive Sample Th1 Polarization Human PBMC Purification Protein A Concentration 0. 2 mg ml Conjugation FITC Physical Appearance Liquid Storage Buffer PBS, 1%

Product Specification


Host Human
Antigen GM-CSF
Synonyms Granulocyte-macrophage colony-stimulating factor; Colony-stimulating factor (CSF); Molgramostin; Sargramostim; GMCSF; CSF2
Location Secreted
Accession P04141
Clone Number S-2816
Antibody Type Recombinant mAb
Application ICFCM
Reactivity Hu
Positive Sample Th1 Polarization Human PBMC
Purification Protein A
Concentration 0.2 mg/ml
Conjugation FITC
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
ICFCM 5μl per million cells in 100μl volume Hu

Background

Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as CSF2, is a multifunctional glycoprotein cytokine that serves as a critical regulator of hematopoiesis and immune responses by binding to a specific heterodimeric receptor complex composed of an alpha chain (CD116) and a shared beta chain (CD131) on target cells. Primarily produced by activated macrophages, T cells, mast cells, endothelial cells, and fibroblasts in response to inflammatory stimuli, GM-CSF stimulates the proliferation, differentiation, survival, and functional activation of myeloid progenitor cells, driving their development into mature granulocytes (such as neutrophils, eosinophils, and basophils) and monocytes/macrophages while simultaneously enhancing the antimicrobial and antigen-presenting capabilities of these mature cells through mechanisms like increased phagocytosis, oxidative burst, and upregulation of MHC class II molecules. Beyond its physiological role in boosting host defense against infections and maintaining tissue homeostasis, GM-CSF plays a significant pathological role in chronic inflammatory and autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis, where its overproduction contributes to sustained inflammation and tissue damage, making it a prominent therapeutic target for monoclonal antibodies aimed at blocking its signaling pathway, while recombinant forms of the protein (e.g., sargramostim) are clinically utilized to accelerate myeloid recovery following chemotherapy or bone marrow transplantation.

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SKU: 6360789387

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4.8 ★★★★★
Based on 1857 reviews
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Mark
Port Orchard, US
★★★★★ 5
Hallelujah… finally, I found the right pillow!!!
Size: Queen (Pack of 1), Color: White
I have spent a lot of money searching for the right pillow. I recently tried to Tempur-pedic that cost twice with this pillow cost. Tempur-pedic flattened out. I’ve had this pill for a few weeks now and it works wonders. I am a paraplegic. You can have a lot of neck problems. I love the fact that this pillow is adjustable. I immediately saw it was too stuffy and took a bunch out. It works perfect so glad I didn’t spend money on a $200 purple pillow. I read a lot of reviews and there were a lot of complaints about the odor. Mine did smell funny when it came out of the box. I immediately threw it in the dryer with a few bounce fabric sheets came out smelling fine. Pillows are a very individual thing, but I think for 40 bucks this pillow is worth a try. I’m really enjoying mine about one of those silk pillowcases to go over it and it sleeps cool and comfortable. Best wishes in your search for the right pillow. Update: I’ve been using this pillow several months and it continues. Give me a good night rest pain-free.. well worth the money. UPDATE: I have been using this pillow for three months and it still works great. It does not flat out or get hot..
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Reviewed in the United States on January 29, 2026
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Verified Purchase
Danica Mandic
Los Angeles, US
★★★★★ 5
Soft comfortable very good pillow
Size: King (Pack of 1), Color: White
I really love my new pillow it's great and comfortable. Yes, it has a little smell, but if you wash the pillowcase and put the pillow on the window for a day you won't notice anything anymore.
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Reviewed in the United States on May 18, 2026
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Verified Purchase
Zachery Jeffries
Louisville, US
★★★★★ 5
Best place for head
Size: Queen (Pack of 1), Color: White
Do you love not getting sleep and sweating all over your pillow at night when you are asleep? If so then don't buy this pillow! If you want a good nights sleep and cool pillow like me this is the one. Ive always been ehh towards spending so much on a pillow but its 100% worth it, I sleep so much better and it forms to my head and keeps me cool at night. Great support even for my big head and comes with a bag of extra stuffing if you want to have a little more firmer pillow. Highly recommend
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Reviewed in the United States on April 4, 2026
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Verified Purchase
Loves_2_read
Lexington, US
★★★★★ 3
Oversized
Size: Queen (Pack of 2), Color: White
I have chronic neck pain. I am forever buying new pillows. Sometimes I think I found the perfect pillow but then three months later they’re losing their loft. I thought I would give these pillows to try since the stuffing is removable. Now these pillows are really oversized. To the point where I thought that they had sent me king-size pillows but I double checked the packaging and they were Queen. I ended up having to buy king-size pillowcases for them because they just barely fit in the queen size and the pillowcases would always end up pulling back from the edge. So that’s a negative one star there. Now I’ve been sleeping on these pillows for a while and they have held up well. I did end up removing some of the stuffing because it was just too much. I’m a side sleeper and when I use this pillow, it does a good job of keeping my neck in alignment. However, the pillow tends to migrate up as I sleep. Or I tend to slip down off the pillow, either or. So that’s why I’ve removed a second star. Maybe if I removed more stuffing that wouldn’t happen, but then I feel like the loft would be too little. I will say that these provide great support when sitting up in bed reading or watching TV. So would I buy them again? Probably not. Am I going to keep using them? Yes
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Reviewed in the United States on December 23, 2025
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Verified Purchase
Nick
Boise, US
★★★★★ 5
Amazing - Stop Scrolling and Buy This Pillow
Size: Queen (Pack of 1), Color: White
I have been an Amazon customer ever since the very beginning, and this is my first review. Not because I haven’t purchased tons of amazing things (and a few bad ones), just never felt the need. However, I researched pillows for longer than I care to admit, and decided on this one. I’ve had it for about six months and absolutely love it. No lie, I genuinely look forward lying my big head on it after a long day. I am a side sleeper, but flip flop all around through the night and it’s great in every position. Pros: Stays nice and cool, which is soothing regardless of the time of year. Has a sort of quilted textured pattern on the zip up cover, gives it a luxury feel, that breaths nicely even when a pillow case is added. The fill is fully adjustable to your preference. I knew it came with extra filling but was worried it would not be enough. Wrong. It was very full and I ended up taking some out until it was perfect. It comes vacuum sealed and suggests it may take some time to fully take shape. However, I found it to be about 90% almost instantly and was sleeping on it a couple hours later. There was no unpleasant scent sometimes associated with memory foam items. The foam itself is very nice, a mix of what appears to be shredded and cotton candy cloud like. Very brilliant idea, as it is somehow supportive, soft and firm all at once. The affordability of this pillow compared to some of the others in this category can’t be overstated. Oh, and the packaging was very thoughtfully and securely done. If you are like me, an over thinker, I would suggest just taking this for a spin. It’s amazing. I’m not a bot, or working for the company. I’m just truly satisfied, love this pillow, and have been sleeping great.
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Reviewed in the United States on April 6, 2026

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