SKU: 33126682447

BRF 45™

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Description

BRF 45™Productinformatie Designs for Health BRF 45 is een geavanceerde vitamine K formule ter ondersteuning van de botgezondheid. Het supplement bevat een klinisch relevante dosering van vitamine K2 (als MK 4), aangevuld met vitamine K1 en GG Gold (geranylgeraniol). Deze combinatie is ontwikkeld om botremodelleringsprocessen (Bone Remodeling Factors, BRF) te ondersteunen bij zowel vrouwen als mannen. Wat is BRF 45? BRF 45 is een hooggedoseerde vitamine K

Productinformatie

Designs for Health BRF 45™ is een geavanceerde vitamine K-formule ter ondersteuning van de botgezondheid. Het supplement bevat een klinisch relevante dosering van vitamine K2 (als MK-4), aangevuld met vitamine K1 en GG-Gold® (geranylgeraniol). Deze combinatie is ontwikkeld om botremodelleringsprocessen (Bone Remodeling Factors, BRF) te ondersteunen bij zowel vrouwen als mannen.

Wat is BRF 45™?

BRF 45™ is een hooggedoseerde vitamine K-formule die zich richt op het behoud van sterke botten en een gezonde vaatstructuur. De formule is specifiek samengesteld om leeftijds- en hormoongerelateerde veranderingen in de botstofwisseling te ondersteunen, zoals tijdens de menopauze en andropauze.

Wat doet vitamine K2 (MK-4)?

Vitamine K2 in de vorm van menaquinon-4 (MK-4) speelt een rol bij het activeren van eiwitten die betrokken zijn bij het botmetabolisme en de calciumhuishouding. MK-4 wordt vaak toegepast in hogere doseringen vanwege de specifieke rol bij botremodellering en vaatgezondheid.

Wat is GG-Gold® (geranylgeraniol)?

GG-Gold® is een natuurlijk extract uit annattozaad (Bixa orellana) en levert trans-geranylgeraniol, een stof die betrokken is bij de endogene aanmaak en omzetting van vitamine K-verbindingen. Het wordt toegevoegd ter ondersteuning van de werking van vitamine K in het lichaam.

Voordelen van BRF 45™

De onderstaande gezondheidsclaims zijn in afwachting van goedkeuring door de EFSA.

BRF 45™ kan bijdragen aan:

  • Ondersteuning van normale botgezondheid en botsterkte*
  • Het behoud van een gezonde calcium- en collageenbalans in botten*
  • Ondersteuning van botremodelleringsprocessen*
  • Behoud van arteriële elasticiteit en vaatintegriteit*
  • Extra ondersteuning bij een verhoogde behoefte aan vitamine K, bijvoorbeeld bij gebruik van bepaalde medicatie*

*Gezondheidsclaims in afwachting van goedkeuring door de Europese Commissie

Waarom kiezen voor Designs for Health BRF 45™?

✔ Bevat 45 mg vitamine K2 (MK-4) – klinisch relevante dosering
✔ Met vitamine K1 (1000 mcg) voor aanvullende ondersteuning
✔ Met GG-Gold® uit annattozaad
✔ Gericht op botgezondheid én vaatgezondheid
✔ Vrij van gluten, zuivel en soja
✔ Non-GMO
✔ Professionele kwaliteit van Designs for Health

Samenstelling per dagdosering (2 softgels)

Ingrediënt Hoeveelheid % RI
Vitamine K1 (fytonadion) 1000 mcg 1333 %
Vitamine K2 (menaquinon-4, MK-4) 45 mg
Trans-geranylgeraniol (GG-Gold® uit annattozaad) 30 mg

✝ RI niet vastgesteld

Overige ingrediënten:
Medium chain triglycerides (MCT), rundergelatine, glycerine, gezuiverd water.

Vrij van

✗ Gluten
✗ Zuivel
✗ Soja
✗ GMO’s

Gebruik en dosering

Neem 2 softgels per dag bij een maaltijd.
Gespreide inname over de dag wordt aanbevolen.

Waarschuwing

Raadpleeg vóór gebruik een deskundige bij gebruik van antistollingsmedicatie zoals warfarine of coumadine.
Een voedingssupplement is geen vervanging voor een gevarieerde voeding en gezonde leefstijl.

Veelgestelde vragen

Voor wie is BRF 45™ geschikt?

BRF 45™ is geschikt voor volwassenen die hun botgezondheid en vaatfunctie willen ondersteunen, met name bij veroudering of hormonale veranderingen.

Waarom bevat dit supplement zowel vitamine K1 als K2?

Vitamine K1 en K2 hebben verschillende functies binnen het lichaam. De combinatie ondersteunt zowel de algemene vitamine K-status als specifieke bot- en vaatprocessen.

Is BRF 45™ geschikt bij medicijngebruik?

Bij gebruik van bloedverdunners dient altijd eerst overleg plaats te vinden met een zorgprofessional.

Inhoud: 60 softgels
Merk: Designs for Health
Herkomst: Verenigde Staten

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SKU: 33126682447

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A
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Ashley Burns
Phoenix, US
★★★★★ 5
Sun kissed without the sun damage!
Color: Ultra Dark, Size: 16 Fl Oz (Pack of 1), Color: Ultra Dark, Size: 16 Fl Oz (Pack of 1)
I’m officially obsessed with this self tanner. The glow is unreal! Super natural, bronzy, and not even a hint of orange. It gives that “just got back from vacation” look without the sun damage. It actually smells GOOD while applying, which is rare for self tanners. Typical self tanner smell once it sets. It goes on clear, which I love because there’s zero transfer onto clothes or sheets. The only downside is that since there’s no guide color, it can be a little tricky to see where you’ve already applied it, so take your time and blend well. But honestly... The end result is flawless, even, glowy skin. 100% a staple for me now!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 17, 2026
D
Verified Purchase
Dallas
Draper, US
★★★★★ 4
Good lasting color
Color: Ultra Dark, Size: 16 Fl Oz (Pack of 1)
I have been a big fan of this brand for quite a while. I do like this specific one. The smell is not over baring however I always mix any self tanner with lotion or oil to help it go on more evenly as well as masks and possible unappealing smell. It does not rub off on clothes unless your sweating then it may but I refrain from wearing white the first day I apply but after that it’s no problem. Color is good for me. I’m fair skinned so it doesn’t so it works well for me. But the downside to that is it can be more noticeable when it starts to fade because it doesn’t fade evenly. It fades as your skin cells slough off so a good exfoliating shower helps with that. Then reapply! And the color last longer then most other brands I’ve tried
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 23, 2026
H
Verified Purchase
Herbert salinas
Whiting, US
★★★★★ 5
Great gel self tanner !!
Color: Ultra Dark, Size: 16 Fl Oz (Pack of 1)
This stuff is insane!!!! It literally looks and goes on clear but!!! After an hour after it being on ur skin ur are instantly tan!!! No bad strong smell and the tan last forever and it don’t look fake or streaky at all. This stuff gives you a bronze glow and natural tan not orangey at all, it’s amazing.
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Reviewed in the United States on June 2, 2026
C
Verified Purchase
C.P.R.
Lexington, US
★★★★★ 3
50/50 - Honest and Fair review
Color: Dark, Size: 16 Fl Oz (Pack of 1), Color: Dark, Size: 16 Fl Oz (Pack of 1)
So… I bought the “glow your own way” in “darkest”. As soon as it came, immediately I read the back for timing instructions… there’s absolutely no mention of time to keep on. To be honest, that turned me off immediately especially for someone that may be new to self tanning, they would have had no idea. I had a little bit of an idea so I went with eight hours, wash off with warm water and apply moisturizer. Says “rinse free” but you have to rinse! The DHA in the tan gel that makes your color darken will only continue to develop over the next 24-30hrs AFTER YOU RINSE OFF! If you do not rinse for an extended period of time thinking the color will make you darker and darker until you look like JLO, the DHA can actually start to diminish, and your skin will begin to dry out being the tanner is now over process. I would not go over 12hrs AT THE MOST before finishing off. That being said, this also didn’t not say if I could rinse with warm water, warm water and soap, a full blown shower, and for someone new to this - they would have no idea. Not cool! Smell - the first pump into my hands was a mix of bad coconuts, tanner, and chemically nauseating but once it was on and dried it was much better. The “fake” tan smell wasn’t as strong as others I’ve used which I very much appreciated. I did my over night so I wasn’t too worried about the smell, if you do tan during the day, your self tanner odor will be noticed. Picture #2 - I did not apply to my hands. My hands are very dry from cleaning, doing dishes, being a mom and wife. The only thing they need is moisturizer so I opted to not apply on my old man hands. I’m coming up on hour eight and you can see the subtle difference between my wrist and my hand color. Hoping the DHA will develop more over the next day and the color will darken (I will let you know if I remember). I did NOT see a huge difference to my light olive complexion and that was disappointing. This gel in “darkest” should have been a great match for my skin tone. Overall the smell was low after applying, the get dried very quickly which was a HUGE bonus to me! At the end of the night, speedy is the best thing for me! The subtle color this gave me was not worth it, I am hoping it darkens up over the next 24hrs. Maybe I got a faulty solution in mine. If you’re a beginner, here’s your guide to timing and rinsing and I wouldn’t say not to try. The clear solution is beneficial and the quick drying was awesome. But if you’re looking for a deep, dark color, you’re not going get it from this which is a bummer. Hope this helped!
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Reviewed in the United States on February 24, 2025
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Verified Purchase
R P
Birmingham, US
★★★★★ 5
Long lasting
Color: Dark, Size: 16 Fl Oz (Pack of 1)
This stuff lasts forever, lol It doesn’t smell bad and if you apply it correctly, the tan lasts quite a long time! It’s just a tiny bit too dark for me for every day but great for a vacation. It’s not streaky and it’s not too orange, but it is warm.
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Reviewed in the United States on May 9, 2026

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