SKU: 85913216073

Mouse IL-12 P70 Serum OneStep ELISA Kit

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Description

Mouse IL-12 P70 Serum OneStep ELISA KitProduct Specification Antigen IL 12 Immunogen Recombinant Protein Antibody Type Recombinant mAb Reactivity Ms Purification Protein A Stability & Storage 12 months from date of receipt reconstitution, 2 to 8'C as supplied. Kit Precision Intra assay: 2. 6% Inter assay: 2. 9% Sample type Serum Assay type Sandwich (quantitative) Sensitivity 5. 205 pg mL Range 7. 81 pg mL 500 pg mL Recovery Serum: 99% Assay time 60 minutes Species reactivity Ms Background

Product Specification


Antigen IL-12
Immunogen Recombinant Protein
Antibody Type Recombinant mAb
Reactivity Ms
Purification Protein A
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8'C as supplied.

Kit


Precision Intra-assay: 2.6%;
Inter-assay:2.9%
Sample type Serum
Assay type Sandwich (quantitative)
Sensitivity 5.205 pg/mL
Range 7.81 pg/mL – 500 pg/mL
Recovery Serum: 99%
Assay time 60 minutes
Species reactivity Ms

Background

Mouse IL-12 is a critical pro-inflammatory cytokine that bridges innate and adaptive immunity. It is a heterodimeric protein composed of p35 (IL-12A) and p40 (IL-12B) subunits, forming the bioactive IL-12(p70). Primarily produced by antigen-presenting cells like dendritic cells and macrophages upon pathogenic stimulation, its pivotal role is to drive the differentiation of naïve CD4⁺ T cells into T helper 1 (Th1) cells and to potently induce interferon-gamma (IFN-γ) production from both T cells and natural killer (NK) cells. This establishes a robust cellular immune response essential for defense against intracellular pathogens such as viruses and bacteria. In biomedical research, Mouse IL-12 is a cornerstone for studying Th1-mediated immunity, evaluating vaccine efficacy, investigating antitumor immunotherapy strategies, and modeling autoimmune diseases like experimental autoimmune encephalomyelitis (EAE).

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SKU: 85913216073

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