SKU: 64446662429

Biotinylated KIR2DL5/CD158f Fc&Avi Tag Protein, Human

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Description

Biotinylated KIR2DL5/CD158f Fc&Avi Tag Protein, HumanProduct Specification Species Human Synonyms CD158f Accession Q8N109 Amino Acid Sequence His22 His240, with C terminal hIgG1 Fc and Avitag Expression System HEK293 Molecular Weight 65 72kDa (Reducing) Purity 95% by SDS PAGE Endotoxin <1EU g Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4. Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water after rapid centrifugation. Stability & Storage 12 months from

Product Specification


Species Human
Synonyms CD158f
Accession Q8N109
Amino Acid Sequence His22-His240, with C-terminal hIgG1 Fc and Avitag
Expression System HEK293
Molecular Weight 65-72kDa (Reducing)
Purity >95% by SDS-PAGE
Endotoxin <1EU/μg
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4.
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1.Estefania, E. et al. (2007) J. Immunol. 178:4402. 2.Lanier, L. L. (2005) Annu. Rev. Immunol. 23:225.

Background

Killer cell immunoglobulin-like receptor 2DL5(KIR2DL5), which belongs to the immunoglobulin superfamily, is an inhibitory receptor of NK cells.KIR2DL5 (CD158f) is the most recently identified inhibitory member of human killer-cell Ig-like receptors (KIRs), which enable NK cells to sense self-HLA.KIR2DL5 is encoded by two paralogous genes displaying copy number variation and allelic polymorphism-KIR2DL5A and KIR2DL5B. Functional polymorphisms in both its promoter and its coding regions are critical for understanding the KIR2DL5 role in immunity and its importance for human health.

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SKU: 64446662429

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