SKU: 49467976199

LILRB4/CD85k/ILT3 mFc Chimera Protein, Cynomolgus

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Description

LILRB4/CD85k/ILT3 mFc Chimera Protein, CynomolgusProduct Specification Species Cynomolgus Synonyms Leukocyte immunoglobulin (Ig) like receptor B4,LILRB4, CD85K, ILT3 Amino Acid Sequence Gln22 Glu259, with C terminal Mouse IgG2a Fc

Product Specification


Species Cynomolgus
Synonyms Leukocyte immunoglobulin (Ig)-like receptor B4,LILRB4, CD85K, ILT3
Amino Acid Sequence Gln22-Glu259, with C-terminal Mouse IgG2a Fc YHLDKEGSPAPWDTQNPLEPRNKAKFSIPSMTQHYAGRYRCYYHSHPDWSEDSDPLDLVMTGAYSKPILSVLPSPLVTSGESVTLLCQSQSPMDTFLLFKEGAAHPLPRLRSQHGAQLHWAEFPMGPVTSVHGGTYRCISSRSFSHYLLSRPSDPVELTVLGSLESPSPSPTRSISAAAGPEDQSLMPTGSDPQSGLRRHWEIEGRMDEPRGPTIKPCPPCKCPAPNLLGGPSVFIFPPKIKDVLMISLSPIVTCVVVDVSEDDPDVQISWFVNNVEVHTAQTQTHREDYNSTLRVVSALPIQHQDWMSGKEFKCKVNNKDLPAPIERTISKPKGSVRAPQVYVLPPPEEEMTKKQVTLTCMVTDFMPEDIYVEWTNNGKTELNYKNTEPVLDSDGSYFMYSKLRVEKKNWVERNSYSCSVVHEGLHNHHTTKSFSRTPGK
Expression System HEK293
Molecular Weight 57-74kDa (Reducing)
Purity ＞95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag Mouse Fc Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.

Background

Leukocyte immunoglobulin (Ig)-like receptor B4 (LILRB4) is a member of leukocyte Ig-like receptors (LILRs). LILRB4 is encoded in the leukocyte receptor cluster, which is on human chromosome 19q13.4. The structure and function of LILRs are similar to those of other leukocyte receptor cluster receptors, such as killer cell immunoglobulin-like receptors. Leukocyte immunoglobulin-like receptor (LILRB4) is a kind of inhibitory receptor that plays a key role in immune checkpoint pathways. Inhibitory receptors also participate in achieving balance between activating and inhibitory actions to ensure immune responses to pathogens in the immune system. However, they not only protect the host from autoimmune responses, but also preserve peripheral tolerance. LILRB4 also regulates immune responses, and its role in regulating immune responses is mostly controlled by its ligands.
Shipping Notes
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Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 49467976199

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4.3 ★★★★★
Based on 13 reviews
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R
Verified Purchase
RUBEN ARELLANO
Lowell, US
★★★★★ 5
Indestructible bully toy
Color: Blue
We have a bully that chews through everything, believe it when I say, he loves this n it is still in one piece. Where I put treats in it or not. He’s also able to play tug of war with is brother with this toy. I will be buying additional ones!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 16, 2026
L
Verified Purchase
Lucie P
Waukegan, US
★★★★★ 4
Durable, Dogs love it
Color: Red
My Frenchie is a crazy chewer and can chew up a nylabone in a day, so I was looking for something that would last longer. So far this is holding up, and is pretty durable. Both my dogs like it a lot, it’s easy for them to grasp, and chewable but still very tough material. I suspect at some point it’ll wear down, but not for a while. The size was just as described / expected. Not too small and not too big
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 23, 2025
A
Verified Purchase
Amazon Purchase
Draper, US
★★★★★ 5
Great for aggressive chewers!
Color: Blue
Our aggressive chewers love these! Very durable.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 8, 2026
O
Verified Purchase
Ozark Matt-Man
Waukegan, US
★★★★★ 3
NOT FOR PLAYING CATCH.
Color: Blue
This toy is quite heavy, making it good for a chew toy or for fetch, but not for catch. It could very easily injure your dog as it damned near did mine.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 19, 2026
E
Verified Purchase
e callie
Los Angeles, US
★★★★★ 5
Peanut butter delivery system
Color: Blue
My big dog loves this bone. I run PB down the middle on one side when we go out. He loves it and brings the bone to us when we return to play :gimme that bone.”
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 3, 2026

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