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Description
Biotinylated CD84/SLAMF5 His&Avi Tag Protein, HumanProduct Specification Species Human Synonyms CD84, SLAMF5, LY9B, SLAMF5 Accession Q9UIB8 1 Amino Acid Sequence Lys22 Arg220, with C terminal His and Avitag Expression System HEK293 Molecular Weight 40 50kDa (Reducing) Purity 95% by SDS PAGE & >95% by RP HPLC Endotoxin <0. 1EU g Conjugation Biotin Tag Avi Tag, His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, 5% trehalose, PH7. 4 Reconstitution Reconstitute at 0. 1 1 mg ml according to
Product Specification
| Species | Human |
| Synonyms | CD84, SLAMF5, LY9B, SLAMF5 |
| Accession | Q9UIB8-1 |
| Amino Acid Sequence | Lys22-Arg220, with C-terminal His and Avitag |
| Expression System | HEK293 |
| Molecular Weight | 40-50kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE & >95% by RP-HPLC |
| Endotoxin | <0.1EU/μg |
| Conjugation | Biotin |
| Tag | Avi Tag, His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, 5% trehalose, PH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1. Baidildinova G, Pallares Robles A, Ten Cate V, Kremers BMM, Heitmeier S, Ten Cate H, Mees BME, Spronk HMH, Wild PS, Ten Cate-Hoek AJ, Jurk K. Plasma protein signatures for high on-treatment platelet reactivity to aspirin and clopidogrel in peripheral artery disease. Thromb Res. 2023 Oct; 230:105-118. |
Background
Leukocyte differentiation antigen CD84 is also known as SLAM family member 5 (SLAMF5), which belongs to immunoglobulin (Ig) superfamily. CD84 / SLAMF5 contains one Ig-like C2-type (immunoglobulin-like) domain. CD84 plays a role as adhesion receptor functioning by homophilic interactions and by clustering. CD84 / SLAMF5 increases proliferative responses of activated T-cells. Homophilic interactions enhance interferon gamma/IFNG secretion in lymphocytes and induce platelet stimulation via a SH2D1A/SAP-dependent pathway.
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