SKU: 42610991809

APC Mouse Anti-Human CD45RA Antibody (S-R377)

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Description

APC Mouse Anti-Human CD45RA Antibody (S-R377)Product Specification Host Mouse Antigen CD45RA Synonyms Receptor type tyrosine protein phosphatase C; Leukocyte common antigen (L CA); T200; CD45; PTPRC Location Cell membrane, Synapse Accession P08575 Clone Number S R377 Antibody Type Mouse mAb Isotype IgG2b,k Application FCM Reactivity Hu Positive Sample human PBMC Purification Protein A Concentration 0. 2 mg ml Conjugation APC Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin

Product Specification


Host Mouse
Antigen CD45RA
Synonyms Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen (L-CA); T200; CD45; PTPRC
Location Cell membrane, Synapse
Accession P08575
Clone Number S-R377
Antibody Type Mouse mAb
Isotype IgG2b,k
Application FCM
Reactivity Hu
Positive Sample human PBMC
Purification Protein A
Concentration 0.2 mg/ml
Conjugation APC
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu

Background

CD45RA is a splice variant of the CD45 protein, encoded by the PTPRC gene, and is a transmembrane glycoprotein with receptor-type protein tyrosine phosphatase activity. It contains the exon 4 in its structure, which distinguishes it from other CD45 isoforms like CD45RO. CD45RA is predominantly expressed on naïve T cells, indicating their potential for activation and differentiation into effector and memory T cells. Its unique extracellular domain, composed of fibronectin type III repeats, is crucial for modulating intracellular signaling pathways, particularly the T-cell receptor (TCR) signaling cascade. The presence of CD45RA on proliferating cells also serves as a marker for tracking clonal expansions in immune responses.

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SKU: 42610991809

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4.3 ★★★★★
Based on 25 reviews
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A
Verified Purchase
Amazon Customer
San Leandro, US
★★★★★ 5
The best no sugar natural fiber
Even if you have no problems with your dietary system, fiber is an excellent way to protect your lower GI system. I use the no sugar version as I want the fiber, but I want the extra carbs in the regular version. Regular no sugar is fine, and has no problems with taste. Every so often, I treat myself to this better stevia sweetened version. I don’t take either one 3 times a day, as recommended, but I do take it every morning. If you like the regular sugar free version, give this a try. Since I take it every day, I do like occasionally switching to the better version. Read the labels of your fiber supplement products, if you take them. Very few give you the amount of fiber that this does, and you control exactly how much fiber you want. If you read up on the benefits of adding to your daily fiber intake, you will wonder why you haven’t been adding this to your daily healthy supplements This is a very effective way to protect yourself, and most other products don’t come close!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on August 20, 2021
N
Verified Purchase
Nijjargirl
Waukegan, US
★★★★★ 5
Great product for bloat and regularity
This works! I try to take a big tablespoon in the morning and if Im feeling bloated maybe one at night. Within a day or two, it helps you get regular! And it makes you go..and not loose, runny stool either. It leaves with that “empty stomach” feeling. I have this set up on auto delivery. Its a bit expensive but like that it has stevia, so am willing to pay the extra. It tastes like OJ but drink it asap or it becomes thick and slime like within a few minutes.
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Reviewed in the United States on April 16, 2020
S
Verified Purchase
scjr
Chelsea, US
★★★★★ 5
More expensive and not as sweet as regular Metamucil, but no aspartame
I switched to the Stevia variant of Metamucil to cut down my daily intake of aspartame sweetener. The taste definitely isn’t as sweet and invariably some might not like that. I thought the same initially, but after a few dosages of the less-sweet Stevia Meta I’m now use to the taste. For me—less aspartame in my diet is more important than having an overly sweet product. The product functions the same way and is very effective in keeping you regular and the additional fiber in your diet is very important. Try it, but keep in mind it may take some time getting use to the less sweet flavor.
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Reviewed in the United States on December 5, 2019
J
Verified Purchase
JAD
Port Orchard, US
★★★★★ 5
Incredible…
This stuff is incredible. I used to take a psyllium supplement semi regularly but would always stop after a week or so of getting tired of it. This stevia version of Metamucil is better than any fiber I’ve ever taken. Tastes great, dissolves immediately, works incredibly well, and doesn’t get old or repetitive like other versions. Flavorful but not overly sweet. It’s amazing what it does to your poops too. Unbelievable.
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Reviewed in the United States on October 29, 2022
R
Verified Purchase
Robert F
Alexandria, US
★★★★★ 4
Not real sweet, but no sugar
I have been taking Metamucil with real sugar regularly for 20+ years. I became concerned about the amount of sugar I was consuming daily and cannot tolerate aspartame. So, I jumped to buy this when I saw Stevia. I quickly noticed that this version is not sweet. It’s sort of bitter. Also, the texture is different due to not having sugar granules mixed in. It also converts to a gel like texture quicker. I later noticed you use less of this product per serving than the one with sugar (read the label!). I have found the best way to take this is to very quickly (seconds) consume the serving after adding water. Don’t wait too long. I down it like taking a shot out of a shot glass followed quickly by a glass of water. After a while, I got used to the flavor. Overall, I am pleased I am consuming much less sugar and really don’t notice the change anymore.
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Reviewed in the United States on June 2, 2022

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