CD30/TNFRSF8 Fc Chimera Protein, Mouse
SKU: 41839580047

CD30/TNFRSF8 Fc Chimera Protein, Mouse

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Description

CD30/TNFRSF8 Fc Chimera Protein, MouseProduct Specification Species Mouse Synonyms CD30; CD30KI 1; CD30L receptor; D1S166EKi 1; TNFRSF8 Accession Q60846 Amino Acid Sequence Phe19 Thr281, with C hIgG Fc Expression System HEK293 Molecular Weight 72 95kDa (Reducing) Purity 95% by SDS PAGE Endotoxin <0. 1EU g Physical Appearance Lyophilized Powder Storage Buffer PBS, 5% trehalose, PH7. 4 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water after rapid

Product Specification


Species Mouse
Synonyms CD30; CD30KI-1; CD30L receptor; D1S166EKi-1; TNFRSF8
Accession Q60846
Amino Acid Sequence Phe19-Thr281, with C-hIgG Fc
Expression System HEK293
Molecular Weight

72-95kDa (Reducing)

Purity >95% by SDS-PAGE
Endotoxin <0.1EU/μg
Physical Appearance Lyophilized Powder
Storage Buffer PBS, 5% trehalose, PH7.4
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1. Oflzoglu E. et al. (2009) Adv. Exp. Med. Biol. 647:174
2. Kennedy, M.K. et al. (2006) Immunology 118:143.
3.Tarkowski, M. (2003) Curr. Opin. Hematol. 10:267.

Background

CD30, also known as Ki-1 antigen and TNFRSF8, is a 120 kDa type I transmembrane glycoprotein belonging to the TNF receptor superfamily. Mature mouse CD30 consists of a 264 amino acid (aa) extracellular domain (ECD) with three cysteine-rich repeats, a 27 aa transmembrane segment, and a 190 aa cytoplasmic domain. In contrast, human CD30 includes an additional 90 aa in the ECD and contains six cysteine-rich repeats. CD30 is normally expressed on antigen-stimulated Th cells and B cells. However, it is upregulated in Hodgkin’s disease (on Reed-Sternberg cells), other lymphomas, chronic inflammation, and autoimmunity. CD30 binds to CD30 Ligand/TNFSF8 which is expressed on activated Th cells, monocytes, granulocytes and medullary thymic epithelial cells. In B cells, CD30 ligation promotes cellular proliferation and antibody production in addition to the expression of CXCR4, CCL3,and CCL5. An 85 ‑ 90 kDa soluble form of CD30 is shed from the cell surface by TACE-mediated cleavage. Soluble CD30 retains the ability to bind CD30 Ligand and functions as an inhibitor of normal CD30 signaling.

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SKU: 41839580047

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Product Reviews
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Verified Purchase
Jenny Tilshire
Alexandria, US
★★★★★ 4
Soft and delicious, but pricey (but worth it if you care about health)
Flavor Name: Venison Sticks - Original
Ugh, I wish these weren't so pricey, but I know it's because of the high-quality and I really do care about that. I'm willing to pay a bit more of grass-fed and finished meat. And these are the perfect quick snack. They're delicious, they're not hard and impossible to bite/chew like some meat sticks, and they give you clean nutrition. I didn't find them particularly greasy either. The packaging is impossible to open, but I wonder if I got a bad set - all of them are fully sealed at the top where normally there are two pieces so that you can peel the package open. All of mine require scissors to cut open which is frustrating but not the end of the world. Again, not sure if that's standard packaging or just a flaw on the ones I got. In any case, they are great and I have already repurchased!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on July 20, 2025
A
Verified Purchase
Amy Backenstoe
Belleville, US
★★★★★ 5
DELISH
Flavor Name: Beef Sticks - Jalapeño
My entire family LOVES these meat sticks. You can taste the freshness. The texture is meaty, No greasy film, no nasty ingredients. I was sold after reading about the fermentation process of these meat sticks. Excellent flavor. I’ll never stop eating these. Jalapeño are my favorite, they aren’t too spicy.
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Reviewed in the United States on May 28, 2026
S
Verified Purchase
Sherz
Lexington, US
★★★★★ 5
Ten star quality and hands down the best I've ever had
Flavor Name: Venison Sticks - Original
I had a health practitioner suggest I increase protein intake and add in some game meats (venison, bison, elk) along with beef. I found Paleo Valley venison and beef sticks as a great solution to add these to my diet without a big bite in my budget. Paleo Valley provides several beef sticks that are all tasty and will appeal to a variety of consumer preferences though my personal favorite is the venison. All their sources are grass fed and finished, pasture raised and finished. You can instantly taste the difference in quality with your first bite. The sticks are firm and moist, nicely flavored and are simple to carry around as a quick snack or extra protein boost. I found I have less interest in sugary or carb-filled snacks by eating a quality protein source. Many other brands I've tried are hard, dry, heavily spiced and don't really taste natural. Not so with Paleo Valley. As a company, I found them to be very health conscious and have other supplements available, along with really useful educational tips for a healthier lifestyle. I think it's important to leave good reviews when I find something that's exceptional quality and Paleo Valley fits that bill.
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Reviewed in the United States on September 7, 2025
J
Verified Purchase
JeepnJen
Lake Worth, US
★★★★★ 5
BEST GLUTEN FREE BEEF STICKS!
Flavor Name: Beef Sticks - Original
I have bought these mulitple times and now have decided to become a monthly subscriber. I love the fact of the "natural" ingredients, these are truly GLUTEN FREE with no hidden ingredients. The taste is amazing and has the perfect amount of spices, not to much but by NO means bland either. They are always fresh and last a long time. They are never dry, not one single time.
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Reviewed in the United States on April 19, 2026
T
Verified Purchase
T.J. B
Chelsea, US
★★★★★ 3
Half a bad batch?
Flavor Name: Venison Sticks - Original
Unsure if I got a bad batch, ill explain why I gave it a 3. First four I had had the consistency of a banana and just tasted extremely off. It was oily, greasy, and the texture was just not something I ever experienced, and ive had venison/beef sticks before. It was pretty disgusting I brought them to work to ensure they didnt go to waste and kept one The one I had was perfect flavor, texture, non greasy and exactly what I had expected. Checked with the coworkers I shared them with and theirs were fine. It leads me to believe maybe it was a bad batch? If they were all like the first few id say 0 stars, if they were all like the last id say 5
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Reviewed in the United States on January 30, 2026

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