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Description
IL-9 Protein, HumanProduct Specification Species Human Synonyms Interleukin 9; IL 9; Cytokine P40; T cell growth factor P40; IL9 Accession P15248 Amino Acid Sequence Gln19 Ile144 Expression System E. coli Molecular Weight Approximately 14. 1 kDa, a single non glycosylated polypeptide chain containing 126 amino acids. Purity 97% by SDS PAGE or HPLC. Conjugation Unconjugated Physical Appearance Lyophilized Powder Storage Buffer 20 mM PB, with 150 mM NaCl, pH 7. 4.
Product Specification
| Species | Human |
| Synonyms | Interleukin-9;IL-9;Cytokine P40;T-cell growth factor P40;IL9 |
| Accession | P15248 |
| Amino Acid Sequence | Gln19-Ile144 |
| Expression System | E.coli |
| Molecular Weight | Approximately 14.1 kDa, a single non-glycosylated polypeptide chain containing 126 amino acids. |
| Purity | ＞97% by SDS-PAGE or HPLC. |
| Conjugation | Unconjugated |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | 20 mM PB, with 150 mM NaCl, pH 7.4. |
| Reconstitution |
Before use this product, please read the direction below carefully. This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions. |
| Stability & Storage | For long term storage, the product should be stored ≤ -20℃. |
Background
Interleukin-9 (IL-9) is encoded by the IL9 gene and produced by T-cells and specifically by CD4+ helper cells. IL-9 is an immunoregulatory cytokine enhances the proliferation of T lymphocytes, mast cells, erythroid precursor cells and megakaryoblastic leukemia cell lines. Over-expression of IL-9 has been implicated in the pathogenesis of anaplastic lymphoma and Hodgkin’s disease. Whereas murine IL-9 can function on human cells, human IL-9 is inactive on mouse cells. Recombinant Human IL-9 is a 14.1kDa protein of 126 amino acid, including 10 cysteine that are fully conserved between the human and murine proteins.
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