Mouse Anti-Human CXCR6 Antibody (S-3884)
SKU: 33241568813

Mouse Anti-Human CXCR6 Antibody (S-3884)

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Description

Mouse Anti-Human CXCR6 Antibody (S-3884)Product Specification Host Mouse Antigen CXCR6 Synonyms C X C chemokine receptor type 6; CXC R6; CXCR 6; CDw186; G protein coupled receptor STRL33; G protein coupled receptor bonzo; CD186; BONZO; STRL33; TYMSTR Location Cell membrane Accession O00574 Clone Number S 3884 Antibody Type Mouse mAb Isotype IgG2a,k Application FCM Reactivity Hu Positive Sample Human PBMC Purification Protein A Concentration 2 mg ml Conjugation Unconjugated Physical

Product Specification


Host Mouse
Antigen CXCR6
Synonyms C-X-C chemokine receptor type 6; CXC-R6; CXCR-6; CDw186; G-protein coupled receptor STRL33; G-protein coupled receptor bonzo; CD186; BONZO; STRL33; TYMSTR
Location Cell membrane
Accession O00574
Clone Number S-3884
Antibody Type Mouse mAb
Isotype IgG2a,k
Application FCM
Reactivity Hu
Positive Sample Human PBMC
Purification Protein A
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1:200 Hu

Background

CXCR6 (C-X-C motif chemokine receptor 6), also known as STRL33 and T-lymphocyte-expressed seven-transmembrane domain receptor (TYMSTR), is a G protein-coupled receptor (GPCR) that specifically binds to its unique ligand CXCL16, a transmembrane chemokine that can also be cleaved to function as a soluble chemokine. CXCR6 is predominantly expressed on memory/effector T cells, natural killer T (NKT) cells, natural killer (NK) cells, and plasma cells, playing critical roles in immune cell trafficking, adhesion, and activation. The CXCR6-CXCL16 axis is essential for the recruitment and positioning of immune cells in various tissues, particularly in the liver, spleen, and inflamed sites, and has been implicated in numerous pathological conditions including chronic inflammation, autoimmune diseases, infectious diseases, and cancer. In oncology, CXCR6 expression on tumor-infiltrating lymphocytes (TILs) is associated with improved prognosis in certain cancers, while its expression on tumor cells can promote metastasis and disease progression. The receptor signals primarily through Gαi proteins, activating downstream pathways such as PI3K/AKT, MAPK/ERK, and calcium mobilization, thereby regulating cell migration, survival, and proliferation. Given its selective expression on activated immune cells and its involvement in disease pathogenesis, CXCR6 represents an attractive therapeutic target for immunomodulatory strategies and precision medicine approaches.

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SKU: 33241568813

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Donna Maria Pearson
Dallas, US
★★★★★ 5
Great Safe Can Opener
Color: Black+Grey
The 1️⃣ touch can opener is great⭐️⭐️⭐️⭐️⭐️. It is easy to use & eliminates possible cuts to my hand on those cans that have a pop up lid. I am almost 70 so sometimes using a manual can opener is difficult. Thank you for selling a quality product at a really fair price ⭐️🌈⭐️🌈⭐️Donna Pearson in New Orleans
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Reviewed in the United States on May 23, 2026
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Linda
Port Orchard, US
★★★★★ 4
Great, leaves top of can Very sharp!
Color: Grey Red
Tried it out the second I got it today. Works great. Just know that it leaves the top of the can VERY sharp!!! So if you are scooping things out, use a very long handle like a spatula. Will add another star if it lasts more then 6 months
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Reviewed in the United States on April 8, 2026
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Abate Family
Houston, US
★★★★★ 5
Love it takes up less space and easy to use
Color: Grey Red
The can opener works awesome easy to use and the magnet helps hold the lid after use. Easy to clean and easy to stack to the can. Batter life seems great and the product seems durable no issues. Highly recommend.
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Reviewed in the United States on June 1, 2026
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Christopher Brown
Massapequa, US
★★★★★ 5
So far
Color: Black+Grey
I did have a electric can opener before and that brand didn't really work well at all. With this one I have only opened 3 cans with it so far and it worked perfectly. I am very happy with the product and it is really easy to work with. I didn't know if it was going to work on a bigger can and when I put it on it did the job just like it is supposed too.
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Reviewed in the United States on May 7, 2026
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Pat M
Grantham, US
★★★★★ 3
Frustrating Opener
Color: Black+Grey
I love and hate these at the same time! I have had several and this one will not stop once it has started! Even though there is a button that says start/stop whenever you push it, it just starts it all over again and I can’t get the lid out. Very frustrating.
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Reviewed in the United States on March 25, 2026

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