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Description
IGFBP3 Recombinant rabbit mAb (SDT-086-63)Product Specification Host Rabbit Antigen IGFBP3 Synonyms Insulin like growth factor binding protein 3, IBP 3, IGF binding protein 3, IGFBP 3 Immunogen Recombinant Protein Location Secreted Accession P17936 Clone Number SDT 086 63 Antibody Type Rabbit mAb Application WB Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300 Stability & Storage 12 months
Product Specification
| Host | Rabbit |
| Antigen | IGFBP3 |
| Synonyms | Insulin-like growth factor-binding protein 3, IBP-3, IGF-binding protein 3, IGFBP-3 |
| Immunogen | Recombinant Protein |
| Location | Secreted |
| Accession | P17936 |
| Clone Number | SDT-086-63 |
| Antibody Type | Rabbit mAb |
| Application | WB |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | null |
Background
Insulin-like growth factor-binding protein 3, also known as IGFBP-3, is a protein that in humans is encoded by the IGFBP3 gene. IGFBP-3 is one of six IGF binding proteins. IGFBP-3 was first isolated, characterized, and quantitated in human plasma, in 1986. It has well-documented functions in the circulation, in the extracellular environment, and inside cells. It is the main IGF transport protein in the bloodstream, where it carries the growth factors predominantly in stable complexes that contain the binding protein, either IGF-1 or IGF-2, and a third protein called the acid-labile subunit or ALS. IGFBP-3 levels in human serum are, like IGF-1, dependent on growth hormone (GH); for example, serum IGFBP-3 is increased in acromegaly and low in GH-deficient children. However, IGFBP-3 gene expression in human liver is GH-independent. Because it is stabilized in human serum by forming complexes with IGF-1 and ALS, which are both GH-dependent, serum IGFBP-3 also appears regulated by GH. Its production by some non-hepatic tissues may also be directly GH-regulated. Immunoassays for serum IGFBP-3 are often used as part of the diagnosis of childhood GH-deficiency.
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4.9 ★★★★★
Based on 29 reviews
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Product Reviews
★★★★★ 5
These worked for me!
Color: Original Grey
They worked great. I bought these for cracked sore heels. It took 2-3 weeks but my heels no longer hurt and the cracks have closed and look more like an indention than a crack now. They feel so much better, but I'll probably wear them another week just to be sure they stay healed. They look and feel like regular socks from the outside but only cover the heel with the toe open. Not think but not thick, again like regular socks. They would probably be slippery on a smooth surface the same as socks. The inside feels like rubber or something smooth at the heel. I have washed them once each pair and accidentally dried one pair in the dryer. They still seem to feel the same so I think they're fine. They're pretty inexpensive and had different colors and sizes.
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Reviewed in the United States on February 10, 2026
★★★★★ 4
Truly Helped My Cracked Heels
Color: Original Grey
I didn't include a photo cause they look exactly like their advertisement photo.
I so liked the silicon-type heel lining as it kept the heel-repair cream on my heel and did not get soaked up by the sock. But, it is so, so slippery when walking around in them! Take care to be mindful when you set each foot down as the lotion can slide your heel across the sock quite a bit. If these socks were for an elderly person, I would have them only sit while using the sock - no walking around for fear of falling.
I have larger ankles and found that having both the top and the bottom hems/elastic, etc. the same size to be quite troublesome and was not a nice feeling or fit on my upper hem that hit my ankle. Don't get me wrong, I am so glad that I got them and I continue to use them and they are helping my horribly-cracked heels greatly, but I find that I have to keep moving the top hem up and down so that it doesn't stay in one position as it cuts in to my ankle.
My feedback and advice might be to please make the upper hem somewhat larger than the one that is on the bottom and goes over my actual foot. They really should not be the same circumference...or else make different sizes - S, M, L, etc. That's really my only complaint or "con" to ordering these.
I think they are a great concept and I like the fact that I can throw them in the washer and dryer.
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Reviewed in the United States on June 8, 2024
★★★★★ 5
Actually works, and really well
Color: Original Grey
I bought these because I got them on a great deal and was quite skeptical, but they actually worked exactly as advertised and I saw a huge difference after the first night! I understand why they don’t cover the whole foot like a regular sock (it would be stifling), but it would be incredible if they made a pair that go forward enough to cover the ball of the foot. One pair lasted about 3 weeks before the moisturizer wore out (I did notice a dropoff after washing, so for best results put them on when you’re clean and just for overnight, so you can avoid washing).
Apologies for no photos- no one wants to see the before photos. These work so well I’ve just come back to order more even though I’m now paying full price. Definitely, definitely recommend.
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Reviewed in the United States on May 28, 2026
★★★★★ 5
Comfortably and works
Color: Original Grey
❤️ I used these with magnesium lotion on my heals for 3 nights, soaked my feet every morning and cracked heals are gone!
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Reviewed in the United States on April 25, 2026
★★★★★ 5
A game changer for deep heel cracks and psoriasis!
Color: Original Grey, Color: Original Grey
If you have deep cracks or psoriasis on your heels, get these they are a total game changer! They hold in Vaseline and topical meds perfectly while I sleep, providing much needed relief without getting all over my sheets. My heels are healing faster and my callouses are softer and don’t split open because the moisture is trapped against the skin all night with the built in gel cushion lining instead of rubbing off. So much hydration.
The fact that it is a 2 pack is perfect because while one pair is being washed and drying, you still have a set to wear. Very soft, stretchy, breathable, and easy to sleep in. I highly recommend them!
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Reviewed in the United States on January 31, 2026