SKU: 21095137772

PTK7/CCK4 His Tag Protein, Cynomolgus

Sale price$243.00 Regular price$270.00
Save 10%

Pay in installments of $67.50 with ShopPay, AfterPay and Klarna

Shipping Estimate
USA
  • USA
  • CAN

Ships within 48 hours · Estimated delivery Jul 17 - Jul 22

Promo Codes Available:

For Your Every Summer RSVP, with Code: SUMMER15

Description

PTK7/CCK4 His Tag Protein, CynomolgusProduct Specification Species Cynomolgus Synonyms PTK7, CCK4, Tyrosine protein kinase like 7, Protein tyrosine kinase 7, Protein tyrosine kinase 7 Accession A0A2K5VNI5 Amino Acid Sequence Ala39 Thr712, with C terminal His Expression System HEK293 Molecular Weight 90 100kDa Purity >95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4 Reconstitution Reconstitute at 0.

Product Specification


Species Cynomolgus
Synonyms PTK7, CCK4, Tyrosine-protein kinase-like 7, Protein-tyrosine kinase 7, Protein-tyrosine kinase 7
Accession A0A2K5VNI5
Amino Acid Sequence Ala39-Thr712, with C-terminal His
Expression System HEK293
Molecular Weight 90-100kDa
Purity >95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1、Lichtig H. et al. (2019) Ptk7 proteolytic fragment proteins function during early xenopus development. Dev Biol. 453 (1): 48-55.

2、Damelin M. et al. (2017) A ptk7-targeted antibody-drug conjugate reduces tumor-initiating cells and induces sustained tumor regressions. Sci Transl Med. 9 (372): eaag2611.

3、Berger H. et al. (2017) Ptk7 faces the wnt in development and disease. Front Cell Dev Biol. 5: 31.

Background

PTK7 comprises an extracellular region with seven immunoglobulin (Ig)-like loops, a transmembrane domain, and a cytosolic region containing a defective tyrosine kinase catalytic domain. Previous studies have reported that PTK7 functions as a co-receptor in the semaphorin/plexin signaling pathway, as well as in planar cell polarity and non-canonical Wnt signaling pathways during developmental processes. Additionally, PTK7 is associated with tumorigenesis. The expression of PTK7, which is upregulated in various malignancies, is negatively correlated with disease-free survival and/or overall survival in patients with cancer. PTK7 potentiates oncogenic signaling by functioning as a co-receptor for active RPTKs, such as FGFR1. The expression of PTK7 is also upregulated in endothelial cells, especially during tube formation.
Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 21095137772

Discover Niche Categories That Outsell

Top-Converting Item to Boost Your Average Order

4.7 ★★★★★
Based on 20 reviews
Sort
Highest Rating
Newest First
Oldest First
Product Reviews
P
Verified Purchase
Phil
Grantham, US
★★★★★ 5
TRY IT!
Size: 6 Fl Oz (Pack of 1)
Just try it. It really works well. And makes your hair look natural and not dyed.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 1, 2026
A
Verified Purchase
Anonymous
Omaha, US
★★★★★ 4
Important to know
Size: 6 Fl Oz (Pack of 1)
The product is good but takes a long time to work. I wish the tube was made of a different recyclable material.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 13, 2026
D
Verified Purchase
Dave
Port Orchard, US
★★★★★ 5
Nice Hair Color
Size: 6 Fl Oz (Pack of 1)
Makes my hair look at least 10 years younger. Almost pure white to nice gray brown looks great. many compliments
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 21, 2026
I
Verified Purchase
Ignacio
Alexandria, US
★★★★★ 5
Worth the price
Size: 6 Fl Oz (Pack of 1)
Worth price and the results show up after the first use
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 11, 2026
J
Verified Purchase
J.v.
Waukegan, US
★★★★★ 5
Good price
Size: 6 Fl Oz (Pack of 1)
Good product and price
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 16, 2026

recommand products