SKU: 14685423751

FGF-6 Protein, Human

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Description

FGF-6 Protein, HumanProduct Specification Species Human Synonyms Fibroblast growth factor 6, FGF 6, Heparin secretory transforming protein 2 (HST 2; HSTF 2), Heparin binding growth factor 6 (HBGF 6) Accession P10767 Amino Acid Sequence Gly41 Ile208 Expression System E. coli Molecular Weight 14 15 kDa (Reducing) Purity >95% by SDS PAGE, >90% by HPLC. Endotoxin <0. 1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized powder Storage Buffer PBS, pH7. 4

Product Specification


Species Human
Synonyms Fibroblast growth factor 6, FGF-6, Heparin secretory-transforming protein 2 (HST-2; HSTF-2), Heparin-binding growth factor 6 (HBGF-6)
Accession P10767
Amino Acid Sequence

Gly41-Ile208
Expression System E.coli
Molecular Weight

14-15 kDa (Reducing)
Purity >95% by SDS-PAGE, >90% by HPLC.
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag No Tag
Physical Appearance Lyophilized powder
Storage Buffer

PBS, pH7.4
Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage

·12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
·3 months, -20 to -80℃ under sterile conditions after reconstitution.
·1 week, 2 to 8℃ under sterile conditions after reconstitution.
·Please avoid repeated freeze-thaw cycles.
Reference

Genes & Dev. 1997;11(16):2040-2051.
Nat Commun. 2020;11(1):1421.

Background

Fibroblast growth factor 6 (FGF-6), also designated as HST2 or HBGF-6, is a secreted peptide growth factor belonging to the paracrine FGF subfamily. The FGF6 gene, located on human chromosome 12p13, encodes an 18.9 kDa protein that exhibits the highest expression in skeletal muscle and myogenic progenitor cells throughout embryonic development and adulthood. FGF-6 binds preferentially to fibroblast growth factor receptor 4 (FGFR4) with heparan sulfate proteoglycan co-receptor dependency, triggering downstream signaling through the MAPK/ERK1/2 and PI3K/AKT pathways.Functionally, FGF-6 operates as a dose-dependent regulator of myogenesis, promoting satellite cell proliferation at high concentrations and initiating myogenic differentiation via calcineurin-dependent pathways at lower concentrations. Beyond muscle physiology, FGF-6 exhibits pleiotropic functions in bone remodeling, iron homeostasis, thermogenesis, and oncogenesis, harboring both regenerative and tumorigenic activities.
Shipping Notes
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Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
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SKU: 14685423751

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4.5 ★★★★★
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K
Verified Purchase
Kelly
San Leandro, US
★★★★★ 4
Great case!
Color: Pink
Very cute! Fits amazing and feels very nice. It’s not too thick but it is protective! I bought it for my IPad A16. I got the light pink one and it does get dirtied easier but that’s just how light pink is. The fold is pretty stables. The sleep mode works well. So far I love this case! Very good for the price!
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Reviewed in the United States on December 3, 2025
R
Verified Purchase
RAC
Birmingham, US
★★★★★ 5
Great, once you know the trick, to getting stylus off.off.
Color: Navy Blue
The case is perfect.The only problem is the stylus holder. Apparently there's a trick to getting it out safely. And it makes all the difference in the world. Other than that, the case is just about perfect at a great price.
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Reviewed in the United States on June 3, 2026
M
Verified Purchase
Michel Mitchell
Natrona Heights, US
★★★★★ 5
Quality material
Color: Navy Blue
Sturdy, my IPad fits inside well, it’s secure and well protected. Stylish. Great value
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Reviewed in the United States on May 2, 2026
A
Verified Purchase
Amazon Customer
Bozeman, US
★★★★★ 5
Nice for the price!
Color: Navy Blue
Very nice case for the price! Durable and nice fit!
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Reviewed in the United States on June 11, 2026
J
Verified Purchase
Jan W
Draper, US
★★★★★ 5
Cool Cover
Color: Navy Blue
Love the blue color. Good quality. Just what I needed for my IPad
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Reviewed in the United States on June 11, 2026

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