SKU: 42005902089

Pegylated ultrafine Fe3O4 nanoparticles(High-temperature?Pyrolysis Method)

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Description

Pegylated ultrafine Fe3O4 nanoparticles(High-temperature?Pyrolysis Method)Product Name Name: a>Pegylated ultrafine Fe3O4 nanoparticles(High temperature Pyrolysis Method) Product Overview PEGylated ultra small Fe3O4 nanoparticles (high temperature pyrolysis method) are poor nanomaterials synthesized by high temperature pyrolysis method. The diameter of these nanoparticles is usually less than 10 nanometers (<10 nm), as observed by TEM. Size is generally in the range of 5 10 nm Technical Parameter Composition: Pegylated

Product Name

Name:a>Pegylated ultrafine Fe3O4 nanoparticles(High-temperature Pyrolysis Method)

Product Overview

PEGylated ultra-small Fe3O4 nanoparticles (high-temperature pyrolysis method) are poor nanomaterials synthesized by high-temperature pyrolysis method. The diameter of these nanoparticles is usually less than 10 nanometers (<10 nm), as observed by TEM. Size is generally in the range of 5-10 nm

Technical Parameter

Composition: Pegylated ultrafine Fe3O4 nanoparticles,ultra-pure water

Diameter:<10 nm

Modified group: Methxy, hydroxyl, carboxyl, amino are optional

Note: This Fe3O4 nanoparticle is too small to be attracted to the magnet.

Product Features

Ultra-small size: The size of this type of nanoparticles is usually in the range of 5-10 nm. The ultra-small size helps to improve its diffusion capacity and cellular uptake efficiency in living organisms. PEGylation surface modification: Modifying the surface of nanoparticles with polyethylene glycol (PEG) increases their stability and biocompatibility while reducing non-specific interactions with biomolecules. High-temperature pyrolysis synthesis: One-step synthesis using high-temperature pyrolysis. This method can obtain single-crystal iron nanoparticles with uniform size and good crystallinity. Superparamagnetism: These nanoparticles exhibit superparamagnetic properties with high saturation magnetization, making them suitable for magnetic resonance imaging (MRI) and magnetic hyperthermia therapy (MHT). High biocompatibility: PEGylation improves the compatibility of nanoparticles with biological systems and reduces immune response and toxicity. Long circulation time: PEG modification helps extend the residence time of nanoparticles in the blood circulation and increases their ability to accumulate in diseased sites.

Application Fields

Magnetic resonance imaging (MRI) contrast agent: Due to its superparamagnetism, Fe3O4 nanoparticles can be used as a T2 contrast agent for MRI, reducing the relaxation time of surrounding protons and improving the clarity and accuracy of imaging. Surface modification can improve the biocompatibility and tumor targeting performance of Fe3O4 nanoparticles, ultimately improving MRI imaging signals and therapeutic effects. Magnetic hyperthermia therapy (MHT): Fe3O4 nanoparticles can generate local high temperatures under the action of an external alternating magnetic field and are used for magnetic hyperthermia therapy to treat tumors. Through surface modification, Fe3O4 nanoparticles can enhance their accumulation inside tumors, thereby improving the effect of magnetothermal therapy. Drug delivery system: Fe3O4 nanoparticles can be used as drug carriers, enriched in tumor tissues through the EPR effect, and improve the targeted transport efficiency of drugs. For example, Fe3O4@void@ZnO-DOX nanoparticles designed using a template-assisted method are used for magnetic targeted delivery of drugs to treat tumors. Multimodal imaging and tumor collaborative therapy: Fe3O4 nanoparticles and their derived composite nanomaterials have attracted widespread attention in multimodal imaging and tumor collaborative therapy. Fe3O4 nanoparticles of different sizes can be obtained through different preparation methods, and modification on their surface can improve biocompatibility and tumor targeting performance.

Related Information

Please e-mail for the detailed characterization data.

E-mail:[email protected]

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SKU: 42005902089

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4.8 ★★★★★
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Y
Verified Purchase
ynk
Bozeman, US
★★★★★ 3
No longer as durable
Color: Purple
I have one of these that has made it through 2 dogs but now the bungee is stretched out. It's been such a well loved toy I recently got another one. They've changed the plush fabric. The old one was indestructible. This new one is much thinner and easily torn. I wish they would go back to the old plush fabric.
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Reviewed in the United States on February 4, 2024
D
Verified Purchase
Donna
Houston, US
★★★★★ 5
Great Toy!
Color: Orange
This has been a great toy for our 11 week old German Shepherd. She absolutely loves it. I can get out all of her toys and lay them out with the exception of her "Lizzy" and she will immediately go to her toy bin and get it herself. Needless to say it is her favorite toy. She has had it a week now and she plays with it a lot, chewing and squeaking. It's a pretty amazing toy to have held up this long already and to date shows no sign of wear or damage. Lizzy just keeps going and going.
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Reviewed in the United States on April 4, 2014
A
Verified Purchase
Anna Rita
New York, US
★★★★★ 1
This item came with plush missingand thread unraveling on one leg
Color: Blue
I bought this toy because my dog spent a week playing with the same toy from Zanies that belonged to a visiting dog. My dog was very gentle with this toy, which he loved, so we decided to find one for him. The toy that arrived had no Zanies label and missing plush on the bottom where the label should have been, plus other bare spots in the area that showed the white mesh beneath. It also had a long thread at the joint of a rear leg so I knotted it at the joint and clipped it to prevent my dog from pulling at it but it's apparent that the sewing is loose and wont last long. The color was also much lighter than the toy he'd been playing with that belonged to the guest dog but I figured it might just be from a different dye lot (it was not bought at Amazon but their local pet store.) I am not convinced this is a real Zanies toy. There were two labels in French and it said it was made in China. I am returning this toy and will get a replacement and see how it looks. If it seems like it will fall apart or is not the real thing I will return it immediately. If it has a label and is in good shape and sewn well at the seams I'll revise this review.
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Reviewed in the United States on August 4, 2020
S
Verified Purchase
S. Carter
Los Angeles, US
★★★★★ 5
Great dog toy!
Color: Green
This is my third or fourth purchase of the same toy. My 45 lb super chewer dog loves to chew on this and especially likes to play tug of war. He is very rough on toys and most do not last longer than a few weeks. This toy lasts about 2 years - which is amazing considering my dog plays with it every day. Eventually it breaks in half during a tug of war session, but I don’t consider that a flaw or a problem because we definitely get our money’s worth of playtime! I’m happy to buy a new one every couple of years and I will keep buying it as long as it is available.
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Reviewed in the United States on April 22, 2023
A
Verified Purchase
Ann
Chelsea, US
★★★★★ 5
Still going strong after three months of Doberman teeth!
Color: Green
This was one of the first toys I purchased for my adopted 4 year old Doberman Pinscher. It has been chewed, and chewed, and chewed some more. This is one of his 3 favorite toys when he has to go in his crate. As of yet there are no significant teeth marks, holes, or missing pieces. It is solid rubber, light weight compared to a similar toy he has, and just the right size to carry around in his mouth. He seems to enjoy the sensation the little rubber nubs have on his gums when he chews it. We have also used this toy to play tug of war and fetch for the same reasons listed but also because the neon green color is easy to see especially if the dog gets distracted and leaves it in the yard. When playing fetch the weight of the toy does not lead to rotator cuff surgery with repetitive throwing on the part of the dog's human! When it gets too dirty and slimy for my tolerance, it is easily washed in the laundry room sink with dish detergent and a sponge always returning to its Spic n' Span original appearance. If and when he chews this one up, I will not hesitate to replace it. Top 3 Likes: -Sturdy, holds up to chewing, used as a crate toy as it poses no threat from dislodged pieces -Bright color aids in finding it outside -Comparatively lightweight, easy to throw, and easy to clean Top 3 Disikes: -Potentially an aggressive chewer could dismantle Only 1 dislike!
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Reviewed in the United States on May 23, 2024

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