SKU: 21403797289

mNSET™ (Non-Surgical Embryo Transfer) Device for Mice 60010 (10 Devices per box)

Sale price$187.65 Regular price$208.50
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Ships within 48 hours · Estimated delivery Jul 17 - Jul 22

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Description

mNSET™ (Non-Surgical Embryo Transfer) Device for Mice 60010 (10 Devices per box)mNSET ordered after June 24, 2026 will ship on July 7, 2026 For AI and pathogen transfer, see product 60020. 10 Devices Box ParaTechs mNSET (Non Surgical Embryo Transfer) Device for Mice 60010 revolutionizes mouse uterine embryo transfer by reducing cost and eliminates the need for animal anesthesia and recovery normally required for conventional surgical procedures. Compare this methodology with the time, expense, and training required to accomplish

mNSET ordered after June 24, 2026 will ship on July 7, 2026

For AI and pathogen transfer, see product 60020.

10 Devices/Box

ParaTechs’ mNSET™ (Non-Surgical Embryo Transfer) Device for Mice 60010 revolutionizes mouse uterine embryo transfer by reducing cost and eliminates the need for animal anesthesia and recovery normally required for conventional surgical procedures. Compare this methodology with the time, expense, and training required to accomplish the same task with other methods and you will discover that the NSET procedure is humane, quick, and cost effective.

The mNSET Device for Mice 60010 is manufactured in the USA, solely for ParaTechs Corporation, and is EtO (Ethylene Oxide) sterilization processed. Patent Information: Non-Surgical Embryo Transfer Method and Apparatus, United States Patent 9,615,903. [PDF]

 Harmonized Tariff: 3926.90.9910

Based on user feedback, we would like to emphasize the following observation: 

The mNSET hub must be firmly seated on the P2 pipette to effectively uptake and dispense liquid.  Please be sure to firmly attach the device using pressure and a slight twisting motion.  This will ensure proper placement.

10% Discount on orders of 10 or more boxes. Discount applies automatically at checkout. 


mNSET 60010 Videos

Watch the mouse NSET demonstration videos:

  1. mNSET 60010 Full Procedure Demonstration Video
  2. mNSET 60010 Quick Procedure Only Video

Watch ParaTechs' JoVE article "Inducing Pseudopregnancy in Female Mice Without the Need for Vasectomized Males Prior to Non-Surgical Embryo Transfer or Artificial Insemination"  

  1. Author Spotlight
  2. Cervical Manipulation Procedure for Use with Artificial Insemination in CD1 Mice (CM Rod 90050) (mC&I Device 60020)
  3. Non-Surgical Embryo Transfer Procedure for Use with Cervical Manipulation in CD1 Mice (CM Rod 90050) (mNSET Device 60010)

Inducing Pseudopregnancy in Female Mice Without the Need for Vasectomized Males Prior to Non-Surgical Embryo Transfer or Artificial Insemination JoVE Published: July 7, 2023

mNSET 60010 Webinars

Watch both webinars presented by Dr. Barbara Stone, Director of Rodent Assisted Reproductive Technologies, ParaTechs Corporation

  1. Rodent Embryo Transfer and the 3Rs
  2. The Future of Mouse Embryo Transfer: Achieving the 3Rs with the NSET Device

Labroots Webinar ABSTRACT: Non-surgical transfer techniques for mouse embryos and sperm provide animal welfare benefits for assisted reproduction of mice. While surgical embryo transfer (ET) is an effective method for transfer of embryos into the uterine horn of mice, surgery is expensive, time consuming, and requires technical expertise. Surgery is also a stressful procedure for the mouse, which has to be anesthetized and treated with an analgesic. We have developed a simple, brief procedure for ET using a non-surgical embryo transfer (NSET) device. Once embryos are loaded into the NSET device, the NSET catheter passes through the vagina and traverses the cervix to deposit the embryos into the uterine horn of a recipient mouse. Since the NSET procedure does not require sedation, opening of the inner body cavity, or use of an analgesic, this procedure is less stressful for the mouse than surgery. In proof, our results show that when pseudopregnant mice are monitored by electrocardiography, the non-surgical procedure does not affect heart rate. The NSET procedure also has no effect on the level of the stress biomarker fecal corticosterone measured by ELISA analysis. However, surgery or anesthesia does lower heart rate and increases levels of fecal corticosterone. Additional studies show that the NSET procedure is effective for transfer of mouse embryos for the purposes of rederivation, cryorecovery, and transgenic research. Embryos can be successfully transferred with the NSET technique after cryopreservation, in vitro fertilization (IVF), or embryonic stem (ES) cell injection as an alternative to traditional surgical embryo transfer. The NSET device has also successfully transferred mouse sperm for artificial insemination. Therefore, the NSET technique is an example of a 3Rs refinement, an alternative to a surgical procedure, which will lead the way for improved assisted reproductive techniques in mice. 


Uses

Mouse Embryo Transfer:

  • Embryo transfer after DNA microinjection
  • ES cell chimeric blastocyst transfer
  • Cryopreserved embryo transfer
  • Embryo transfer after in vitro fertilization
  • Embryo transfer for rederivation

Other:

  • Small volume material transfer to the uterine horn.  For larger volume transfer, please consider the mC&I device which has a 40µl capacity. 
  • Mouse Sperm Transfer for Artificial Insemination (AI): Fresh sperm
  • Pathogen Transfer: Chlamydia trachomatis
  • Material Transfer:
    • Decidualization procedures
    • Pharmaceuticals

Advantages

  • Eliminates the pain and distress of surgery
  • No anesthesia required
  • Eliminates need for post-surgical monitoring of animals
  • Reduces regulatory burden by eliminating need to justify survival surgery
  • Eliminates surgical instruments and time-consuming pre- and post-surgical processes
  • Greatly reduces time required to become proficient in embryo transfer or artificial insemination (AI)
  • Reduces costs of embryo transfer
  • Reduces costs of AI
  • Easy procedure
  • Convenient
  • Sterile and ready to use
  • 3Rs implementation (Reduce & Refine)

Documents

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 21403797289

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Renee M. Willimas
Waukegan, US
★★★★★ 5
Cute denim, nice leather ties, awesome price and fits as they should. Would buy again.
Size: 8.5 Wide, Color: Linen Navy
ordered 8 1/2 W since toe box is fairly narrow. Fits perfectly. Cute with jeans, leggings and shorts. Decent arch support, nice soles and SUPER value for the price (These are 80 at shoe stores locally) Would buy again.
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Skribbles76
Carnegie, US
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Comfy and cute.
I was looking for a Converse alternative for a multitude of reasons. These were perfect. I love the slip-on style. The leather laces stay in place much better than the Converse cotton laces and there is way more sole support, which is a huge plus. I purchased these in black about a year ago and then went for the camo pair. As for the black pair, I wore them regularly for a year. After that time, the shoe didn't feel as comfortable anymore, and the fabric outer around the ankle began to fray, and the white outer trim was beginning to detach from the bottom sole. With that, I was pleased with how long they lasted. As for the camo pair, I anticipate the same quality and comfort. While super cute, the only draw back is the mismatched pattern. If you look at the pics, the one shoe has more gold embellishment at the toe area and the other one doesn't. This bothers me a bit as I would have liked it to match. Otherwise, I'm happy with both purchases so far and will continue to buy them in the future.
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Doris Stanley
Lake Worth, US
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Love these shoes. Great value and comfortable
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Texas 12
Whiting, US
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Long lasting. Sperry is quality.
Last a long time and still look good.
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I love these it's been a while since I bought them and still look like brand new.
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Reviewed in the United States on February 12, 2026

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